WHAT IS THE DIFFERENCE BETWEEN ANTIPHOSPHOLIPID SYNDROME AND MONOCLONAL GAMMOPATHY?: GET THE ANSWER FROM HARVARD HEALTH PUBLISHING.

Answered by Dr. Robert H. Shmerling

M.D. Senior Faculty Editor, Harvard Health Publishing · 30 years of experience · USA

Antiphospholipid syndrome is a condition in which a person has abnormal antibodies and either an increased tendency to form blood clots or an increased tendency to have miscarriages. The abnormal antibodies in this condition come in 3 main forms: lupus anticoagulant, anti-cardiolipin antibodies and anti-beta2-glycoprotein. Monoclonal gammopathy is a condition in which there is an abnormally high production of a specific type of antibody. This can be associated with a malignancy, such as multiple myeloma, or, as is the case in up 3% of older adults, it may be present with no symptoms or organ damage (a condition called monoclonal gammopathy of undetermined significance, or MGUS). There is no clear association between antiphospholipid syndrome and monoclonal gammopathy although persons with autoimmune disease, such as lupus erythematosus/in-systemic lupus erythematosus?ocid=feed-health-article" target="_blank">systemic lupus erythematosus, may have both antiphospholipid syndrome and MGUS.

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2024-05-03T15:07:56Z dg43tfdfdgfd