Enlarged Spleen Mononucleosis can cause swelling in the spleen. Which can raise the risk of a rupture of the organ if too much pressure is applied [something that might happen in a fall or from someone bumping into you] Which is why doctors. Recommend avoiding strenuous activity and contact sports while recovering.
One may spread to the other individuals. Progressive splenomegaly secondary to mononucleosis is having a high risk of rupture. Hypersplenism can be noted. It may lead to pneumonia, myocarditis, myositis, acute renal failure.
If left untreated, the infection cause enlarged spleen and it may rupture resulting in sudden severe pain in your upper abdomen.
→ Learn more about infectious mononucleosis: See the causes, symptoms, treatment options and more.
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